Shadia I. Jalal, MD
Associate Professor of Medicine
Address
Indiana Cancer Pavilion
535 Barnhill Dr., Suite 473
RT 473
Indianapolis, IN 46202-5289
535 Barnhill Dr., Suite 473
RT 473
Indianapolis, IN 46202-5289
Titles & Appointments
- Associate Professor of Medicine
- Lawrence H. Einhorn Scholar in Oncology
- Program Leader - Thoracic Oncology
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Education2009 Fellowship Indiana University School of Medicine2006 Residency Indiana University School of Medicine2006 MD University of Jordan2002 MBBS University of Jordan
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PublicationsThe Case for Maintenance Pemetrexed Plus Bevacizumab.
Hanna N; Jalal S; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2020 Jan 2An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function.
Ramchandani NK; Kesler KA; Rogers JD; Valsangkar N; Stokes SM; Jalal SI; Journal of visualized experiments : JoVE 2020 Apr 17Pembrolizumab alone or in combination with chemotherapy as first-line therapy for patients with advanced gastric or gastroesophageal junction adenocarcinoma: results from the phase II nonrandomized KEYNOTE-059 study.
Bang YJ; Kang YK; Catenacci DV; Muro K; Fuchs CS; Geva R; Hara H; Golan T; Garrido M; Jalal SI; Borg C; Doi T; Yoon HH; Savage MJ; Wang J; Dalal RP; Shah S; Wainberg ZA; Chung HC; Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2019 Mar 25Acceptance and Commitment Therapy for Symptom Interference in Advanced Lung Cancer and Caregiver Distress: A Pilot Randomized Trial.
Mosher CE; Secinti E; Hirsh AT; Hanna N; Einhorn LH; Jalal SI; Durm G; Champion VL; Johns SA; Journal of pain and symptom management 2019 Jun 28Breakthroughs and challenges in the management of tropomyosin receptor kinase fusion-positive tumors.
Mamdani H; Jalal SI; Annals of translational medicine 2019 JulPembrolizumab After Two or More Lines of Previous Therapy in Patients With Recurrent or Metastatic SCLC: Results From the KEYNOTE-028 and KEYNOTE-158 Studies.
Chung HC; Piha-Paul SA; Lopez-Martin J; Schellens JHM; Kao S; Miller WH Jr; Delord JP; Gao B; Planchard D; Gottfried M; Zer A; Jalal SI; Penel N; Mehnert JM; Matos I; Bennouna J; Kim DW; Xu L; Krishnan S; Norwood K; Ott PA; Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2019 Dec 20A phase 2, open-label study of brentuximab vedotin in patients with CD30-expressing solid tumors.
Sharman JP; Wheler JJ; Einhorn L; Dowlati A; Shapiro GI; Hilton J; Burke JM; Siddiqi T; Whiting N; Jalal SI; Investigational new drugs 2019 Apr 16Doppler fluctuation spectroscopy of intracellular dynamics in living tissue.
Li Z; Sun H; Turek J; Jalal S; Childress M; Nolte DD; Journal of the Optical Society of America. A, Optics, image science, and vision 2019 Apr 1Social correlates of mental health in gastrointestinal cancer patients and their family caregivers: Exploring the role of loneliness.
Secinti E; Rand KL; Johns SA; O'Neil BH; Helft PR; Shahda S; Jalal SI; Mosher CE; Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2018 Sep 17Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial.
Fuchs CS; Doi T; Jang RW; Muro K; Satoh T; Machado M; Sun W; Jalal SI; Shah MA; Metges JP; Garrido M; Golan T; Mandala M; Wainberg ZA; Catenacci DV; Ohtsu A; Shitara K; Geva R; Bleeker J; Ko AH; Ku G; Philip P; Enzinger PC; Bang YJ; Levitan D; Wang J; Rosales M; Dalal RP; Yoon HH; JAMA oncology 2018 May 10Outcomes of a novel intrathoracic esophagogastric anastomotic technique.
Kesler KA; Ramchandani NK; Jalal SI; Stokes SM; Mankins MR; Ceppa D; Birdas TJ; Vardas PN; Rieger KM; The Journal of thoracic and cardiovascular surgery 2018 Jun 8Spotlight on the treatment of <i>ALK</i>-rearranged non-small-cell lung cancer.
Mamdani H; Jalal SI; Lung cancer management 2018 Jun 22Coping Skills Practice and Symptom Change: A Secondary Analysis of a Pilot Telephone Symptom Management Intervention for Lung Cancer Patients and Their Family Caregivers.
Winger JG; Rand KL; Hanna N; Jalal SI; Einhorn LH; Birdas TJ; Ceppa DP; Kesler KA; Champion VL; Mosher CE; Journal of pain and symptom management 2018 Jan 31Pembrolizumab in combination with ipilimumab as second-line or later therapy for advanced non-small-cell lung cancer: KEYNOTE-021 cohorts D and H.
Gubens MA; Sequist LV; Stevenson JP; Powell SF; Villaruz LC; Gadgeel SM; Langer CJ; Patnaik A; Borghaei H; Jalal SI; Fiore J; Saraf S; Raftopoulos H; Gandhi L; Lung cancer (Amsterdam, Netherlands) 2018 Dec 17Abemaciclib in Combination with Single-Agent Options in Patients with Stage IV Non-Small Cell Lung Cancer: A Phase Ib Study.
Kim ES; Kelly K; Paz-Ares LG; Garrido P; Jalal S; Mahadevan D; Gutierrez M; Provencio M; Schaefer E; Shaheen M; Johnston EL; Turner PK; Kambhampati SRP; Beckmann R; Hossain A; John WJ; Goldman JW; Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Aug 6Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
Jamieson SM; Tsai P; Kondratyev MK; Budhani P; Liu A; Senzer NN; Chiorean EG; Jalal SI; Nemunaitis JJ; Kee D; Shome A; Wong WW; Li D; Poonawala-Lohani N; Kakadia PM; Knowlton NS; Lynch CR; Hong CR; Lee TW; Grénman RA; Caporiccio L; McKee TD; Zaidi M; Butt S; Macann AM; McIvor NP; Chaplin JM; Hicks KO; Bohlander SK; Wouters BG; Hart CP; Print CG; Wilson WR; Curran MA; Hunter FW; JCI insight 2018 Aug 2324-Month Overall Survival from KEYNOTE-021 Cohort G: Pemetrexed and Carboplatin with or without Pembrolizumab as First-Line Therapy for Advanced Nonsquamous Non-Small Cell Lung Cancer.
Borghaei H; Langer CJ; Gadgeel S; Papadimitrakopoulou VA; Patnaik A; Powell SF; Gentzler RD; Martins RG; Stevenson JP; Jalal SI; Panwalkar A; Yang JC; Gubens M; Sequist LV; Awad MM; Fiore J; Saraf S; Keller SM; Gandhi L; Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2018 Aug 21Safety and Antitumor Activity of the Anti-Programmed Death-1 Antibody Pembrolizumab in Patients With Advanced Esophageal Carcinoma.
Doi T; Piha-Paul SA; Jalal SI; Saraf S; Lunceford J; Koshiji M; Bennouna J; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017 Nov 8Carboplatin/nab-Paclitaxel and Pembrolizumab for Patients with Advanced Non-Small Cell Lung Cancer (NSCLC): Phase 1 Results.
Gentzler RD; Mohindra NA; Hanna N; Chae YK; Jalal SI; Hall R; Villaflor VM; Reckamp KL; Koczywas M; Sullivan D; Wood L; Patel JD; International journal of radiation oncology, biology, physics 2017 May 1Carboplatin and Etoposide With or Without Palifosfamide in Untreated Extensive-Stage Small-Cell Lung Cancer: A Multicenter, Adaptive, Randomized Phase III Study (MATISSE).
Jalal SI; Lavin P; Lo G; Lebel F; Einhorn L; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017 Jun 12Examining the effect of peer helping in a coping skills intervention: a randomized controlled trial for advanced gastrointestinal cancer patients and their family caregivers.
Mosher CE; Secinti E; Johns SA; O'Neil BH; Helft PR; Shahda S; Jalal SI; Champion VL; Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2017 Jun 10Separation and dual detection of prostate cancer cells and protein biomarkers using a microchip device.
Huang W; Chang CL; Brault ND; Gur O; Wang Z; Jalal SI; Low PS; Ratliff TL; Pili R; Savran CA; Lab on a chip 2017 Jan 31Phase 1 study of narnatumab, an anti-RON receptor monoclonal antibody, in patients with advanced solid tumors.
LoRusso PM; Gounder M; Jalal SI; André V; Kambhampati SRP; Loizos N; Hall J; Holzer TR; Nasir A; Cosaert J; Kauh J; Chiorean EG; Investigational new drugs 2017 Feb 4Spontaneous Pneumothoraces and Hemothoraces in Sarcomas.
Ezzeddine F; Jalal S; Cureus 2017 Dec 3Blood-based tumor biomarkers in lung cancer for detection and treatment.
Mamdani H; Ahmed S; Armstrong S; Mok T; Jalal SI; Translational lung cancer research 2017 DecCarboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study.
Langer CJ; Gadgeel SM; Borghaei H; Papadimitrakopoulou VA; Patnaik A; Powell SF; Gentzler RD; Martins RG; Stevenson JP; Jalal SI; Panwalkar A; Yang JC; Gubens M; Sequist LV; Awad MM; Fiore J; Ge Y; Raftopoulos H; Gandhi L; KEYNOTE-021 investigators.; The Lancet. Oncology 2016 Oct 10Randomized Pilot Trial of a Telephone Symptom Management Intervention for Symptomatic Lung Cancer Patients and Their Family Caregivers.
Mosher CE; Winger JG; Hanna N; Jalal SI; Einhorn LH; Birdas TJ; Ceppa DP; Kesler KA; Schmitt J; Kashy DA; Champion VL; Journal of pain and symptom management 2016 Jul 9Small-molecule binding sites to explore protein-protein interactions in the cancer proteome.
Xu D; Jalal SI; Sledge GW; Meroueh SO; Molecular bioSystems 2016 Jul 25DNA repair targeted therapy: The past or future of cancer treatment?
Gavande NS; VanderVere-Carozza PS; Hinshaw HD; Jalal SI; Sears CR; Pawelczak KS; Turchi JJ; Pharmacology & therapeutics 2016 Feb 16Small Cell Lung Cancer.
Bernhardt EB; Jalal SI; Cancer treatment and research 2016Locally Advanced Non-Small Cell Lung Cancer: Optimal Chemotherapeutic Agents and Duration.
Mamdani H; Jalal SI; Hanna N; Current treatment options in oncology 2015 OctNovel therapies in small cell lung cancer.
Mamdani H; Induru R; Jalal SI; Translational lung cancer research 2015 OctConcurrent Detection of Cellular and Molecular Cancer Markers Using an Immunomagnetic Flow System.
Huang W; Chang CL; Chan BD; Jalal SI; Matei DE; Low PS; Savran CA; Analytical chemistry 2015 Jul 24Adjuvant Epidermal Growth Factor Receptor Inhibitors in Non-Small Cell Lung Cancer.
Lourdes LS; Jalal SI; Hanna N; The oncologist 2015 Aug 12Circulating tumor cell detection using a parallel flow micro-aperture chip system.
Chang CL; Huang W; Jalal SI; Chan BD; Mahmood A; Shahda S; O'Neil BH; Matei DE; Savran CA; Lab on a chip 2015 Apr 7Treatment of clinical T2N0M0 esophageal cancer.
Hardacker TJ; Ceppa D; Okereke I; Rieger KM; Jalal SI; LeBlanc JK; DeWitt JM; Kesler KA; Birdas TJ; Annals of surgical oncology 2014 Jul 22Exploring a structural protein-drug interactome for new therapeutics in lung cancer.
Peng X; Wang F; Li L; Bum-Erdene K; Xu D; Wang B; Sinn AA; Pollok KE; Sandusky GE; Li L; Turchi JJ; Jalal SI; Meroueh SO; Molecular bioSystems 2014 Jan 9Barriers to mental health service use and preferences for addressing emotional concerns among lung cancer patients.
Mosher CE; Winger JG; Hanna N; Jalal SI; Fakiris AJ; Einhorn LH; Birdas TJ; Kesler KA; Champion VL; Psycho-oncology 2014 Feb 3Gastroesophageal junction adenocarcinoma displays abnormalities in homologous recombination and nucleotide excision repair.
Dewalt RI; Kesler KA; Hammoud ZT; Baldridge L; Hattab EM; Jalal SI; Lung Cancer (Auckland, N.Z.) 2014 Feb 15Coping with physical and psychological symptoms: a qualitative study of advanced lung cancer patients and their family caregivers.
Mosher CE; Ott MA; Hanna N; Jalal SI; Champion VL; Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2014 Dec 20Phase I Study of Amrubicin and Cyclophosphamide in Patients With Advanced Solid Organ Malignancies: HOG LUN 07-130.
Jalal SI; Hanna N; Zon R; Masters GA; Borghaei H; Koneru K; Badve S; Prasad N; Somaiah N; Wu J; Yu Z; Einhorn L; American journal of clinical oncology 2014 Dec 10Support service use and interest in support services among lung cancer patients.
Mosher CE; Hanna N; Jalal SI; Fakiris AJ; Einhorn LH; Birdas TJ; Kesler KA; Champion VL; Lung cancer (Amsterdam, Netherlands) 2013 Aug 6Pulmonary Langerhans cell histiocytosis masquerading as adenocarcinoma of the lung.
Khawaja MR; Ulbright TM; Jalal S; Clinical advances in hematology & oncology : H&O 2013Economic and social changes among distressed family caregivers of lung cancer patients.
Mosher CE; Champion VL; Azzoli CG; Hanna N; Jalal SI; Fakiris AJ; Birdas TJ; Okereke IC; Kesler KA; Einhorn LH; Monahan PO; Ostroff JS; Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2012 Sep 4Support service use and interest in support services among distressed family caregivers of lung cancer patients.
Mosher CE; Champion VL; Hanna N; Jalal SI; Fakiris AJ; Birdas TJ; Okereke IC; Kesler KA; Einhorn LH; Given BA; Monahan PO; Ostroff JS; Psycho-oncology 2012 Sep 3Erlotinib and bevacizumab in newly diagnosed performance status 2 or elderly patients with nonsquamous non-small-cell lung cancer, a phase II study of the Hoosier Oncology Group: LUN04-77.
Riggs H; Jalal SI; Baghdadi TA; Bhatia S; McClean J; Johnson C; Yu M; Taber D; Harb W; Hanna N; Clinical lung cancer 2012 Oct 24DNA repair: from genome maintenance to biomarker and therapeutic target.
Jalal S; Earley JN; Turchi JJ; Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Sep 9Updated survival and outcomes for older adults with inoperable stage III non-small-cell lung cancer treated with cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel: analysis of a phase III trial from the Hoosier Oncology Group (HOG) and US Oncology.
Jalal SI; Riggs HD; Melnyk A; Richards D; Agarwala A; Neubauer M; Ansari R; Govindan R; Bruetman D; Fisher W; Breen T; Johnson CS; Yu M; Einhorn L; Hanna N; Annals of oncology : official journal of the European Society for Medical Oncology 2011 Dec 9Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatin.
Neher TM; Bodenmiller D; Fitch RW; Jalal SI; Turchi JJ; Molecular cancer therapeutics 2011 Aug 16Paclitaxel plus bevacizumab in patients with chemosensitive relapsed small cell lung cancer: a safety, feasibility, and efficacy study from the Hoosier Oncology Group.
Jalal S; Bedano P; Einhorn L; Bhatia S; Ansari R; Bechar N; Koneru K; Govindan R; Wu J; Yu M; Schneider B; Hanna N; Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010 DecPemetrexed plus cetuximab in patients with recurrent non-small cell lung cancer (NSCLC): a phase I/II study from the Hoosier Oncology Group.
Jalal S; Waterhouse D; Edelman MJ; Nattam S; Ansari R; Koneru K; Clark R; Richards A; Wu J; Yu M; Bottema B; White A; Hanna N; Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009 NovThe role of maintenance chemotherapy in advanced nonsmall cell lung cancer.
Jalal SI; Ademuyiwa FO; Hanna NH; Current opinion in oncology 2009 MarPemetrexed in second line and beyond small cell lung cancer: a Hoosier Oncology Group phase II study.
Jalal S; Ansari R; Govindan R; Bhatia S; Bruetman D; Fisher W; Masters G; White A; Stover D; Yu M; Hanna N; Hoosier Oncology Group.; Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009 Jan -
Board CertificationsAmerican Board of Internal Medicine - Medical OncologyAmerican Board of Internal Medicine - Internal Medicine
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